The possible role of circulating ferritin
نویسنده
چکیده
Iron absorption in man is inversely related to body iron stores and serum ferritin concentration. A negative correlation between intestinal iron absorption and the amount of storage iron in the body has been confirmed in the rat and the hypothesis that absorption may be regulated through the mediation of ferritin has been tested. There was no difference in mucosal iron uptake or absorption between rats undergoing a jugular infusion of ferritin and those infused with saline despite a hundredfold difference in circulating ferritin concentration.
منابع مشابه
Evaluation of the Relationship between Serum Ferritin Level and Renal Function in Patients with Thalassemia Major
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متن کاملSerum ferritin.
(1) Brief introduction to iron metabolism and the biochemistry of ferritin. (2) Early studies of circulating ferritin. (3) Methods for measuring serum ferritin concentrations -- immunoradiometric, radioimmuno- and enzyme-linked immuno assays based on liver or spleen ferritin -- an evaluation of these techniques. (4) Serum ferritin concentrations in normal subjects -- definition of normality -- ...
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T ype 2 diabetes is characterized by variable degrees of vascular dysfunction (1,2). We have recently reported improved vasomotor responses in high-ferritin type 2 diabetic patients following bloodletting (3), an intervention that is believed to reduce the deleterious effects of circulating iron on vascular function (4,5). Insulin-like growth factor binding protein–related protein 1 (IGFBP-rP1)...
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Background Regarding abnormalities in thalassemia major (TM) patients and the effects of leptin and ferritin on heart, aimed to investigate the possible relationship between leptin, ferritin and cardiac involvement in TM patients compared to controls. Materials and Methods In total 141 individuals entered to the present case-control study that consisted of 66 TM patients matched in ag...
متن کاملSerum iron and ferritin levels in alopecia areata
Background: Alopecia Areate (AA) is a recurrent non-scarring patchy hair loss of autoimmune origin in a genetically susceptible individual although environmental factors may be contributory. The aim of this study is to evaluate serum iron and ferritin levels in patients with AA. Methods: Fifty patients of AA and 50 age and sex matched control subjects without any hair loss were studied. Results...
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تاریخ انتشار 2006